She served as the Minister of Rural Development and Lands for nearly five years, and is past president of the Bartolina Sisa National Federation of Campesino Women of Bolivia.

She was appointed to the Ministry by President Evo Morales in January 2010, following a long career of union leadership in her native Santa Cruz.

When allegations of widespread corruption in the disbursements from the Indigenous Fund emerged in December 2013, Achacollo was called to testify on the issue.

Despite increasing calls for her to resign, she received a vote of confidence from the Plurinational Legislative Assembly in March 2015.

[2] She resigned her position as Minister on August 31, 2015, continuing to deny criminal responsibility for multi-million-Boliviano losses to the fund.