"[4] This caused concern at DC Comics, the publisher of Batman, but Millar denied there had been threats of legal action: One of my friends at DC legal dropped me an informal email back in December saying that someone in editorial was a bit worried by the Batman and Joker mentions in an interview to promote a creator-owned book.

[10] A follow-up miniseries, titled Nemesis: Reloaded, launched in January 2023 with Jorge Jimenez serving as artist, with the series serving as a soft reboot of the character, helping to better integrate the character into the greater Millarworld shared universe, with a new Matthew "Nemesis" Anderson being trained by Wesley "The Killer II" Gibson.

Following the conclusion of Reloaded, Nemesis then appeared in Big Game, a crossover with every Millarworld property illustrated by Pepe Larraz in July the same year.

Nemesis hijacks Air Force One over the District of Columbia, taking the United States president hostage and crashing the plane into Washington D.C., killing hundreds.

Nemesis reveals to his henchmen that his real name is Matt Anderson, and his father had committed suicide after Morrow tried to imprison him for hunting runaway teenagers with his rich friends.

Bored of well-behaviour and less excitement, Anderson travelled the world to learn the ways of crime, hoping to fulfil his mother's dying wish to have Morrow killed.

Nemesis releases the children but he has artificially inseminated Morrow's daughter with the son's sperm, with her womb rigged to collapse if an abortion is attempted.

Nemesis reveals that his "Matthew Anderson" story was made up: he is simply rich and bored, creating death and havoc for his own amusement.

Nemesis reveals they are in the White House's Oval Office, where Morrow's wife Peggy and the U.S. president have bombs strapped to their chests.

There he is given a letter, ostensibly given to the waiter ten years earlier, congratulating Morrow and claiming to be from the head of a company that arranges for rich people to become supervillains.

The comic ends with the owner of the company (revealed as an older Wesley Gibson in Nemesis: Reloaded) sitting on the beach, enjoying the sunset.

He was disappointed by the artwork, saying it accentuates the shortcomings of Millar's script, finding McNiven's minimalistic style less impressive than his work on Old Man Logan.

[20] Phillips gave issue #3 the same score, describing the comic as "somewhat entertaining" but "not the least bit clever, witty, tasteful, sophisticated or original".

[21] Nicholas Yanes of SciFiPulse.net called the premiere issue "fantastic" and argued that while the series lacked heart in comparison with Millar's Kick-Ass, "this works to point out that the real world is not run by good intentions, but by selfish motivations, ego, and pride.

[26] Mark Millar has seen the script for Nemesis in Autumn 2013 and has given praise to Joe and Matthew's take on his comic book character, stating the film is going to be "massive".