Neonatal pustular eruptions are a group of disorders characterized by various forms of pustulosis (rashes consisting at least in part of pustules) seen in the first four weeks of life.
Neonatal pustular eruptions can be further divided into noninfectious and infectious causes, and range from benign to life-threatening.
[3] The non-infectious causes are generally benign and self-limited.
[4] Most commonly these are primary cutaneous infections, caused by Staphylococcus aureus or beta-hemolytic streptococci.
Congenital syphilis is another bacterial infection of the skin that can cause pustules in the neonatal period.