Nesrin Sipahi was born to Yusuf and Adile in Yeşilköy neighborhood of Bakırköy ilçe (district), Istanbul, Turkey on 29 November 1934.
Following a short marriage in 1950, she remarried to Hasan Aldemir Sipahi on 23 January 1957.
In 1953, she entered Ankara Radio, which was considered as the main music training center at that time.
In her 1971-tour in the Soviet Union, she also sang in Azerbaijani, Russian and Armenian in addition to Turkish.
She performed in the United States, Germany, France, Canada, Australia, Morocco, Tunisia, Syria, Egypt, Cyprus and Spain.