Net 25 has been reaching television audiences on the United States, Canada, numerous Asian and European countries, Australia and New Zealand, as well as the Middle East and North Africa.

[8][9] Prior to this, during the network's news update, then-Net 25 newscaster Eunice Mariño and then-INC spokesperson Bienvenido Santiago announced that Manalo died at the age of 84.

[11] On January 4, 2014, Net 25 introduced a new station ID with a simple blue text superimposed on a Philippine eagle-inspired logo.

[18] On February 8, 2022, Net 25 covered the campaign events of then-presidential candidate and former senator Bongbong Marcos and then-vice presidential candidate and then-Davao City mayor Sara Duterte held in the Philippine Arena, Ciudad de Victoria, Bocaue, Bulacan during the network's primetime news program, Mata ng Agila.

[20] Net 25, with the help of GEMNET, had the first digital and full HD coverage of the 2010 Philippine elections via the ISDB-T system through their sister station's frequency, Channel 49.

It previously carried programs like Call for Help, Fresh Gear, Extended Play, NET Café, Next Step, Computer Chronicle and Audio File.

[26] Net 25 has also featured a number of Korean dramas, including The Snow Queen, Class 7 Civil Servant,[27] Flower I Am, Never Twice,[28] A Place in the Sun,[29] Fatal Promise,[30] Mysterious Personal Shopper, Unwanted Family,[31] House of Bluebird,[32] and Gracious Revenge.