Most of Mixco is separated from the City by canyons, for which a multitude of bridges have been created.

Due to its close proximity to Guatemala City, several villages were turned into residential neighborhoods.

From the residential neighborhoods is excluded "La Florida", which separated from Mixco to join Guatemala City in 1958.

Deportivo Mixco football club play in the Guatemalan second division.

[4] Mixco has a subtropical highland climate (Köppen: Cwb).