Neuronium was founded in 1976 as a psychedelic rock quintet with a percussionist, bassist, guitarist and two synthetists.

Later, synthesist/guitarists Michel Huygen and Carlos Guirao, and guitarist Albert Giménez changed style to so-called "cosmic music", recording the album Quasar 2C361, released in Spain in 1977 by the label EMI-Harvest.

Thereafter, Huygen became the only constant member of Neuronium, with occasional collaborations from guitarist Santi Picó.

[3] The Spanish artist Tomás C. Gilsanz created cover art for the band's albums and the images projected on the stage background during live performances.

[4] Neuronium Records was created in 2002 as Huygen's personal label, which released works from artists such as Suzanne Ciani, Constance Demby, Jonn Serrie, and The Lab.