SR 726 begins at a junction with U.S. Route 95 (US 95) approximately 2 miles (3.2 km) north of downtown Fallon.

From there, the highway runs northeastward along Old River Road, a two-lane roadway following the Lower Soda Lake Drain through a rural agricultural area.

After about 0.8 miles (1.3 km), SR 726 turns onto Bafford Lane, another two-lane farm road.

The highway follows Bafford Lane due east for about 1 mile (1.6 km), ending at a bridge over the Carson River.

[1][3] However, SR 1A was rerouted to a newer alignment by 1957, thus removing the designation from Old River Road.