Route 110 is 15.9-kilometre (9.9 mi) long highway in New Brunswick, Canada; running from the Canada–US border crossing at Bridgewater, Maine as a continuation of Boundary Line Road, a connector to U.S. Route 1 (US 1).

[2] Route 110 beings at the Bridgewater - Centreville Border Crossing in Centerville as a continuation of Boundary Line Road, a local road to downtown Bridgewater, Maine.

The route runs along the bank of the Big Presque Isle Stream, passing a junction with Royalton Road, which connects to the community of Lower Royalton.

Running as a two-lane road through Centreville, the route bends northeast, passing the Centreville Community School and gaining the name Centre Street at the intersection with Route 560 in the center of the village.

Route 110 leaves Centreville and enters rural Carleton County.