It continues north for about 8.4 miles (13.5 km) through Brookline and crosses into Milford, where it meets an interchange with New Hampshire Route 101.

NH 13 continues north over the Souhegan River on the Colonel John Shepard Bridge, then turns northwest for 4.4 miles (7.1 km) towards Mont Vernon and serves as the town's main road.

It turns north at the intersection of New Hampshire Route 114 with which it briefly runs concurrently over the Piscataquog River and into downtown Goffstown.

After taking a sharp right at the intersection, NH 13 heads northeast towards Concord for 4.0 miles (6.4 km) until it reaches the interchange with Interstate 89 near a New Hampshire State Police barracks.

NH 13 then turns north on South Street near downtown Concord, where it meets its northern terminus at US 202/NH 9.