[1] The road passes by The Shops at Ledgewood Commons, the Roxbury Mall, and many other businesses, also crossing the Dover and Rockaway River Railroad's High Bridge Branch.

[2] The route crosses the Dover and Rockaway River Railroad's Chester Branch before it enters Randolph, where the road becomes less commercial in nature and passes Randolph Lake, reaching an interchange with Sussex Turnpike (CR 617).

Route 10 widens to six lanes and then runs through the southwestern corner of Denville before heading into the Mount Tabor section of Parsippany.

[2] Route 10 crosses the Passaic River into Livingston, Essex County, where it becomes Mt.

The route enters West Orange at the point it crosses Nance Road.

[1] In West Orange, Route 10 ends at the intersection of Prospect Avenue where the radio station 1560 WFME's studios and 94.7 WXBK's transmitter facilities are located.

[1][2] Route 10 roughly follows a portion of an old Lenape Trail from the Passaic River to Whippany.

[9] A year later, in the 1953 New Jersey state highway renumbering, Route 10 was defined onto its current alignment, with its eastern terminus moved to Prospect Avenue in West Orange.

[10][11] In 1998, the Ledgewood Circle at the western terminus of the route was replaced with a signalized T-intersection.