State Road 65 (NM 65) is a state highway in the US state of New Mexico.

Its total length is approximately 15.5 miles (24.9 km).

NM 65's northern terminus is a continuation as County Road 263 (CR 263) at the intersection of Forest 156 Road.

It passes through Montezuma, and its southern terminus is at NM 329 in Las Vegas.

The entire route is in San Miguel County.