[1][2] Initially the Hospital served as a foundling home and provided care for New York's working women and their children.

"[5] Its stated mission was: In 1854, a hospital was founded under the name, "The Nursery for the Children of Poor Women," by DuBois and Emmit.

[5] In 1899, the New York Infant Asylum consolidated with the Marion Street Maternity Hospital.

[5] According to an Annual Report, its work consisted of:[5] During the 1930s the hospital was in financial trouble and on November 21, 1934 it was absorbed by the New York Hospital-Cornell Medical Center.

[6] Its specialty departments were discontinued and their services were taken on by other New York City institutions.