At this intersection, NY 60 turns northward through Kiantone, changing names to Foote Avenue as it enters the city of Jamestown.

NY 60 is at this point a four-lane commercial arterial through the southern end of the city, passing to the west of Allen Park and soon bending to the northwest, where it forks off Foote Avenue onto NYS Arterial Highway, passing to the north of Fenton Park.

After the interchange, the route continues northward as North Main Street Extension, passing Moon Brook Country Club.

[5] Through Charlotte, NY 60 continues northward as a two-lane local road, entering the hamlet of Moons, which consists of a few farms and residences.

A short distance after, NY 60 leaves Charlotte for the town of Stockton and into the village of Cassadaga, where it gains the moniker of South Main Street.

Paralleling the nearby Upper Lake, the route leaves the village for the town of Pomfret, becoming a two-lane roadway through woods and some residences through the hamlet of Shumla.

[5] Leaving Laona, NY 60 continues northward through a rural backdrop bending to the north at an intersection with Lakeview Road.

After this point, NY 60 enters the village of Fredonia, where it gains the moniker of Bennett Road after a roundabout intersection with US 20 (East Main Street).

The route passes some businesses before crossing under a former New York Central Railroad line[8] currently used by CSX Transportation.

[16] NY 60 was realigned in the early 1960s to bypass Fredonia to the east on a newly upgraded highway leading from Laona to Reed Corners (US 20).

From there, NY 60 was to follow a new highway to a point on Central Avenue near where it passes under the New York State Thruway, where it would continue into Dunkirk on its original alignment.

[citation needed] NY 60 has been particularly prone to a large number of automobile crashes that lead to fatalities.

The high traffic on the two-lane highway, which is the main road between Jamestown and Dunkirk, makes it difficult and dangerous for vehicles to pass.