[1] When approaching O'Connell Drive, motorists can turn left to continue their journey along the route.

[2] Route 450 made headlines in Newfoundland in January 2018 when massive rainfall caused flooding on January 13 and created a huge crater causing a large portion in the highway to collapse, thus separating residents in Lark Harbour and York Harbour from the remainder of the island.

It heads west along the southern edge of the city to have an intersection with Wheelers Road, which provides access to the Grenfell Campus.

Route 450 now passes through the Curling section of town before leaving Corner Brook before winding its along the southern shore of Humber Arm to pass through Mount Moriah (where it crosses Cooks Brook), Humber Arm South (where a couple of turns are needed to stay on the highway, one to the right, and the other to the left), and York Harbour, all within the rugged terrain of the Lewis Hills portion of the Long Range Mountains.

The highway now enters Lark Harbour and passes by Blow Me Down Provincial Park before passing through town, where it has an intersection with a local road leading to Bottle Cove and Little Port, before the pavement (and Route 450) comes to an end at the eastern edge of town.