Route 80, also known as Trinity Road, is a 105-kilometre-long (65 mi) north–south highway along the Avalon Peninsula of Newfoundland.

It connects the communities along the eastern side of Trinity Bay with the Trans Canada Highway (TCH).

The highway now winds its way through New Perilcan, Turks Cove, Winterton, Hant's Harbour, and New Chelsea-New Melbourne-Brownsdale-Sibley's Cove-Lead Cove before arriving in Old Perlican at an intersection with Route 70 (Conception Bay Highway).

Route 80 turns north through town along Blow Me Down Road for a short distance before ending at an intersection with Marine Drive and Main Street.

Marine Drive continues north to the Harbour while Main Street continues on to Daniel's Cove and Grates Cove.