Niš-Ekspres (full legal name: Akcionarsko društvo za saobraćajnu delatnost Niš-Ekspres Niš) is a bus company based in Niš, Serbia.

Established in 1951, the company is today the largest and most-used public intercity transportation from Niš.

The company was established on 3 March 1951 as Preduzeće za putnički saobraćaj with a fleet composed of seven buses.

They developed their first model, tourist coach Nibus 350 powered by MAN engine.

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