She made her television debut in a Mr Kipling advert before joining the ITV soap opera Coronation Street (2017) as Lara Cutler.

[1] Prior to studying acting, Blackshaw trained as a dancer, and at the age of eleven, she began attending Rossendale Dance and Drama Centre, where she completed her LAMDA and Trinity exams.

[11] On 4 September 2018, it was announced that she would be joining the Channel 4 soap opera Hollyoaks as Juliet Nightingale, and she made her first appearance on 21 November 2018.

[12] Her storylines in the soap included discovering her father is Mac Nightingale (David Easter),[13] being groomed into a county lines drug trafficking gang,[14] coming out as a lesbian[15] and developing a romance with Peri Lomax (Ruby O'Donnell).

[18] After a cancer storyline was devised for her character, it was announced that Blackshaw would be leaving her role as Juliet in 2023, after five years on Hollyoaks.