Nicholas Crispo, Patrizio Veneto (or Niccolò; 1392–1450), became Lord of Syros in 1420 and Regent of the Duchy of the Archipelago between 1447 and 1450.
In a letter dated 1426 Crispo says he was married to the daughter of Jacopo Gattilusio, lord of Lesbos.
In a 1474 chronicle by the Venetian traveller Caterino Zeno it is said that he was married to an Eudoksia Valenza, of whom there is no other mention in any source.
An account by Caterino Zeno dated to 1474 names Niccolò as married to an otherwise unknown Valenza, sister of Theodora Megali Komnene, daughter of John IV of Trebizond.
Whether this means Niccolò took a second wife or whether Zeno was in error has been debated by genealogists This article about Greek history is a stub.