Nicholas Serracino (1877–1934), AIA, was an American architect active in late-nineteenth- and early twentieth-century New York City.

He was principally noted for his designs of churches and parish schools for the Roman Catholic Archdiocese of New York.

[1] He designed St. Jean Baptiste Church and Rectory (1910), one of few Catholic churches in city with a dome and the only one besides St. Patrick's Cathedral (New York City) to have stained glass made in Chartres.

This won a prize in an international competition.

This was followed by the more modest brick temple-fronted Church of the Sacred Hearts of Mary and Jesus (New York City), built in 1915 for $35,000 and demolished in 2007.