Nichols is a town in Tioga County, New York, United States.

[3] The Sullivan Expedition of 1779 passed through the area, destroying the native settlements of those who sided with the British against America in the Revolutionary War .

The Southern Tier Expressway (New York State Route 17 and future Interstate 86) passes across the town south of the Susquehanna River.

The racial makeup of the town was 99.03% White, 0.39% Black or African American, 0.19% Asian, 0.04% Pacific Islander, and 0.35% from two or more races.

20.4% of all households were made up of individuals, and 9.4% had someone living alone who was 65 years of age or older.