It features playable characters from Nickelodeon shows including SpongeBob SquarePants, Invader Zim, The Ren & Stimpy Show, Danny Phantom, Planet Sheen, Avatar: The Last Airbender, Fanboy & Chum Chum, T.U.F.F.

Real Monsters, Hey Arnold!, The Angry Beavers, CatDog, El Tigre: The Adventures of Manny Rivera, Back at the Barnyard, and The Mighty B!

In addition to Nickelodeon characters, the game also features players from real Major League Baseball teams.

For quick play games, 5 Nicktoons characters that have special abilities can be selected by each side.

Once the player beats a certain team or does something major in a baseball game or Distance Derby, a card is unlocked.

"[4] Official Xbox Magazine gave the game a score of 6.5 out of 10, saying "Nicktoons MLB is fun but frivolous, which should work just fine for kids and families".

They also both praised and criticized the usage of Kinect, saying "having your arm angle determine the pitch type is downright genius — though sadly, occasional gaffes (such as seeing swings you didn’t take) muddle the execution".

"[6] Anime Courtyard also gave it a 7 out of 10, stating "At the end we can say that Nicktoons MLB is not spectacular but not a bad option if you want a baseball game without complications.