In Serbian medieval history he is remembered for conveying hesychastic monastic traditions[2] and as a member of a diplomatic and ecclesiastical mission to Constantinople in 1375.

[8] The late Romanian Metropolitan Nestor Vornicescu writes that Nicodemus was a Serb, and that he was fluent in Serbian, Church Slavonic and Greek.

[14] Raised in piety and honesty, early in his youth he met some traveling monks in Serbia from the Hilandar monastery, and went with them to Mount Athos, where he studied and labored patiently with perseverance.

Prince Lazar wanted to appoint him to a high spiritual function, but he rejected it and settled in the eastern parts of the country, near the city of Kladovo on the Danube.

After hearing about his virtuous life, a group of monks gathered around him, and in that place—Manastirica—they established a monastery and a church named "Holy Trinity".

The venerable Nikodim crossed the Danube River and settled in the northern Oltenia, where he erected the Vodice Monastery[17] and dedicated it to Anthony the Great, the founder of Christian monasticism.