Nicola Napolitano (born 22 January 1983) is an Italian footballer who plays for Manfredonia at Lega Pro Seconda Divisione.

Napolitano started his career at hometown club and Italian giant Internazionale.

He made professional debut on 19 December 2002, a Coppa Italia match against Bari.

Since released by Inter in summer 2007, he was signed by Gubbio of Lega Pro Seconda Divisione in January 2008.

This biographical article related to association football in Italy, about a midfielder born in the 1980s, is a stub.