Nicole Khirin (Hebrew: ניקול חירין; born 16 January 2001) is an Israeli tennis player.

She began her collegiate career with the Texas Longhorns.

She won the NCAA championship with the Aggies in 2024, winning the clinching singles point in the final.

Khirin represents Israel at the Billie Jean King Cup, where she has a win–loss record of 1–0.

This biographical article relating to Israeli tennis is a stub.