She also has won one Grand Slam title, winning the mixed-doubles crown at the 2018 Wimbledon Championships with Austrian partner Alexander Peya.

[1][2] Melichar is a two-time Grand Slam tournament finalist in women's doubles, finishing runner-up at the 2018 Wimbledon Championships with Květa Peschke[3] and the 2020 US Open with Xu Yifan.

[4] Melichar made her Fed Cup debut for the U.S. team in 2019, partnering Danielle Collins, losing their match against Australian pair of Ashleigh Barty and Priscilla Hon.

[8] At the 2024 Dubai Championships, she reached her fifth WTA 1000 final with Perez, before losing to fourth seeds Storm Hunter and Kateřina Siniaková.

Only main-draw results in WTA Tour, Grand Slam tournaments, Billie Jean King Cup and Olympic Games are included in win–loss records.