She became famous as a result of her 2005 monologue FUCK YOU, Eu.ro.Pa, which generated controversy in Romania and Moldova.
She worked in a theatre in Chişinău before founding her own company and has directed plays across Europe.
[4] In collaboration with Mihai Fusu and Dumitru Crudu, Esinencu wrote the play A şaptea cafanã (The Seventh Coffee House) and toured it around festivals in 2001.
[6] Esinencu drew attention with her monologue FUCK YOU, Eu.ro.Pa in 2005, winning the Romanian Dramacum theatre award.
Framed as a daughter telling her father why she does not want to enter a Moldovan essay writing competition, it triggered controversy in Romania and Moldova for its frank discussion of post-communism, Moldovan society and the idea of Europe.