She is the anchor of the MSNBC news and politics program Deadline: White House and a former co-host of the ABC daytime talk show The View.

[2][3][4] Together with her three younger siblings, Zachary, Courtney and Ashley,[5] she grew up in Orinda, a San Francisco Bay Area suburb.

[15] In 2003, Wallace joined Bush's 2004 presidential campaign as its communications director, wherein according to The New York Times she "delivered her political attacks without snarling.

"[14] She left the White House in July 2006 to relocate to New York City, where her husband Mark was representing the Bush administration at the United Nations.

[19][20] In response to reports of dissension within the McCain-Palin campaign, Wallace issued a statement to both Politico and CNN saying: "If people want to throw me under the bus, my personal belief is that the most honorable thing to do is to lie there.

Wallace also told ABC News Chief Political Correspondent George Stephanopoulos that the film was "true enough to make me squirm".

"[28] Craig Wilson of USA Today wrote, "Nicolle Wallace actually knows what she's talking about"[29] and Ashley Parker of The New York Times called the book "an engaging, easy read.

"[30] TV personalities, such as George Stephanopoulos,[31] Rachel Maddow,[32] John King,[33] and Andrea Mitchell,[34] also praised Eighteen Acres.

[42] She was also a frequent contributor and guest host on MSNBC programs The 11th Hour with Brian Williams and Morning Joe as well as on NBC's Today Show.

[43] In November 2016, Wallace served as an analyst for MSNBC's live coverage of election results, which was anchored by Brian Williams, Rachel Maddow, and Chris Matthews.

[47] In February 2013, both Wallace and her husband publicly supported the legalization of same-sex marriage in an amicus curiae brief submitted to the U.S. Supreme Court.