The station was opened on 20 August 1863 and is located on the Utrecht–Kampen railway (Centraalspoorweg).

The services are operated by Nederlandse Spoorwegen.

From 1903, Nijkerk was also the northern terminus of the Nijkerk–Ede-Wageningen railway.

The section between Nijkerk and Barneveld was closed and demolished in 1937.

The following train services call at Nijkerk: