[3] 2006 was another strong year for Lewis with the Stampeders as he posting 77 receptions, 1,114 receiving yards and five touchdowns and was named to the 2006 CFL Western Division All-Star team.

[3] Lewis helped lead Calgary to the 96th Grey Cup championship with 87 receptions for 1,109 yards and 10 touchdowns in the 2008 regular season.

[5] In 2011 Nik Lewis partnered with Joffrey Reynolds to create www.calmb4storm.com an organization that gives fans an opportunity to experience things otherwise unattainable.

Lewis subsequently made apologies on two successive days, and announced he was donating the paycheque from his next game (the 2012 Western Final) to a women's charity.

In Week 8 of the 2013 CFL season Lewis suffered a fractured fibula as he was tackled by BC linebacker Solomon Elimimian.

Lewis saw a diminished role in 2014, highlighted by his consecutive games with a catch streak snapped in week 5 against the Edmonton Eskimos.

[10] He posted career-low totals in receiving yards and failed to score a touchdown in any game of the season, also a career low.

Despite the frustrating season, Lewis helped the Stampeders qualify for the 102nd Grey Cup, a game in which he set up Calgary's first touchdown with a 13-yard catch that brought the ball to the one-yard line.

[13] At 34 years of age the Alouettes and Nik Lewis agreed to a two-year contract extension, keeping him with the club through the 2018 season.

[15] On October 27, 2017, Lewis told Lee Jones of TSN that he had played his last game after his Alouettes fell to the Saskatchewan Roughriders, 12–37.