Futterman has provided her voice in many cartoons, including recurring roles on animated adventure and superhero series such as G.I.

Futterman is the voice of Asajj Ventress in the 2008 animated film The Clone Wars and its subsequent TV series as well as several related video games.

She was on the show Behind the Force along with her cast members Ashley Eckstein and James Arnold Taylor with Supervising Director Dave Filoni.

usually only shows up in the songs on the show, the second title character of Fanboy & Chum Chum sings many times (Futterman is also often accompanied on lead vocals during the FB&CC songs by David Hornsby, who voices Fanboy), Stretch and Squeeze of Handy Manny sing two songs called "We Work Together" and "Hop Up, Jump In" alongside the other tools, and Luna Loud of The Loud House is a musician, and frequently sings.

Futterman also performed the vocals as Catwoman for the song, "Birds of Prey" in the Batman: The Brave and the Bold episode, "The Mask of Matches Malone," along with Grey DeLisle and Tara Strong, who voiced Black Canary and Huntress respectively.