Niketas Triphyllios (Greek: Νικήτας Τριφύλλιος; died 30 April 803) was one of the highest officials of the Roman Empire during the reign of empress Irene of Athens (797–802), holding the position of Domestic of the Schools.
At the time, he was already Domestic of the Schools (commander of the elite Scholai regiment) and holder of the supreme dignity of patrikios.
Niketas was one of the four patrikioi (along with Bardanes Tourkos, Constantine Boilas, and Niketas' brother Sisinnios) leading the four white horses which drew the imperial carriage, a role that marks him out as one of the most prominent of Irene's supporters among the high dignitaries of the state.
Staurakios managed to escape with a rebuke from the empress, but took steps to gather armed support to counter Aetios' and Niketas' control of the army's senior officers.
The two camps remained at a stalemate thereafter until February 800, when Staurakios was forbidden to have contacts with the military and Aetios was promoted to the powerful post of strategos of the Anatolic Theme.