Born into a prominent aristocratic family, he was educated at a Greek clerical school in Italy.
From 1608 to 1614, he served later a priest at the court of Teimuraz I, king of Kakheti, eastern Georgia.
In 1625, Teimuraz assigned him to lead an embassy to Europe in order to get support against the Persian aggression.
The mission, however, went in vain; the Europeans at that time were too involved in the Thirty Years' War to be concerned about the fate of a small Christian kingdom in the Caucasus.
After the death of Levan II (1657), Nicholas was arrested by the new prince Vameq III Dadiani, and died in imprisonment in 1658.