Stylistically, Nikortsminda reflects the Georgian cross-dome style of architecture, following a six-conch-within-rectangle plan.

Nikortsminda has a massive dome and unbroken arcatures as its twelve windows, which are decorated with ornamented architraves.

The transition from the hexahedron of the round drum to the dome circle is effected by means of spheric pendentives.

The interior is decorated with frescoes from the 17th century and ornamental sculptural reliefs, reflecting the mastery of the late-Medieval Georgian ecclesiastical art.

Decorations include unbroken arcatures and various rich ornaments, including multiple-figured narrative reliefs and episodes (The Transfiguration, The Judgment Day, The Ascension of the Cross, figures of Saint George and Saint Theodore, real and mythic animals, forming one premeditated program).