In 2013, Ikaros Chalkidas's head coach Georgios Kalafatakis, picked him to join the team that year.

For the 2017–18 season, Persidis moved to Ethnikos Piraeus, which he helped to lead to the Greek 2nd division's playoffs.

Persidis' performances with Diagoras were noticed by the coaching and scouting staff of the Greek EuroLeague club Panathinaikos Athens.

In 23 league games during the 2021-22 campaign, Persidis averaged an improved 4.5 points and 2.2 rebounds, playing around 15 minutes per contest.

Persidis was selected to the Greek national 3x3 team for the 2018 Mediterranean Games, which took place in Tarragona, Spain.