Ricky Ilacad, who was managing director of Warner Music Philippines at the time, listened to the recordings and immediately planned to sign her up even without seeing or hearing her in person.

"[24] "Make You Mine" was described as a "rich harmonic chemistry of Nina's mesmerizing vocals and hypnotic urban-style beats with a blend of funky strings, an upbeat R&B piece that offers a blissful listening experience.

[26] In August 2004, she staged a back-to-back residency at the Music Museum with Nyoy Volante entitled El Niño, La Niña which ended after a month and five shows.

[27] In November 2004, she was chosen by American songwriter Diane Warren to record the Cyndi Lauper original "I Don't Want to Be Your Friend", which eventually became a chart-topping hit.

[19] In the same month, Warner Music Philippines released a Christmas album[28] which features Nina and the label's most-requested singers at the time, namely Christian Bautista, Kitchie Nadal, Dice & K9, Paolo Santos, Thor and Artstrong.

"[50] On the November–December 2006 issue of MYX Mag, Mike Luis of Freestyle reacted positively to the album, stating "The mid-tempo tracks are groove-worthy, the slow jams are sexy, and the two remakes were nicely done.

[52] The song became both a commercial and critical acclaim, with Philippine Daily Inquirer commenting " the introspective, traffic-stopping 'Someday' that boasts of a rich melody and Nina's emotive panache.

In a review, Philippine Daily Inquirer stated "Bonnie Raitt's anthemic song for the lovelorn is hard to top, but Nina gives a beautifully dressed-down version.

"[36][69] In 2009, Nina publicly announced that she would file an estafa (fraud) case against ex-boyfriend Nyoy Volante's parents, Evangeline and Oliver, due to failure in fully settling their debts amounting to ₱1.4 million in total.

"[110] Stay Alive was a universal acclaim, being called "futuristic and edgy" by critics who also predicted that it "may set new trends in Filipino music," tagging Nina as the new "dance diva.

[3] The album was a critical acclaim, with The Philippine Star explaining that its purpose is "not to surpass her previous achievements, but to empower its belief that [Nina] has more to offer as a recording artist.

[138] In February 2015, Nina made a special appearance on the 20th-year anniversary of variety show ASAP where her performance of "Vision of Love" with fellow singers Juris and Kyla became a trending topic in social media.

[139] After taking a break from showbiz, Nina publicly announced her secret marriage with husband Coy Enriquez and giving birth to a baby girl, Ysabelle Louise, on December 24, 2015.

[149] On October 28, 2018, Nina collaborated with David Pomeranz and Joey G on an international concert, entitled Love, Soul & Magic, held at the Club Regent Event Centre, Winnipeg.

[155] On April 16, Nina admitted she became interested in the Korean Wave so much that she stayed in South Korea for a month to undergo K-pop sing and dance workshop.

[159] The following day, she was featured in Monster RX 93.1 Concert Series where she revealed that her management is working on her official YouTube vlog for 2021, and that she has started recording for her upcoming album.

On November 7, Nina was eliminated in TV5 reality singing show Masked Singer Pilipinas after performing "Big Spender" by Shirley Bassey under the alias Bee-Ni-Bee-Ni.

[170] On October 25, 2024, she collaborated with Hindley Street Country Club and released an alternate version of her number-one hit, "Foolish Heart", which eventually reached 1.3 million views in YouTube by the end of same year.

Baby Gil of The Philippine Star described her voice as "sweet but definitely multi-octave," commenting "This is surely her strongest point and it is really a blessing to know that she can skillfully wield her vocals to conform to the demands of every song.

[18] In 2011, Nina was featured in a short documentary aired by South Korean network tvN Asia where she was filmed re-attending the Center for Pop Music of the Philippines for vocal training sessions.

"[196] At the height of its success, the album's format has been adapted in the live recordings of artists including Freestyle,[197] MYMP,[198] Sitti,[199] Christian Bautista,[200] Rachelle Ann Go[201] and Aiza Seguerra.

[183] Music critic Remy Umerez of Journal wrote, "Nina set the bar high for female singers of her generation with the multi-platinum success of her solo albums in the mid-2000s.

"[136] In a review for All Good, Yugel Losorata of The Philippine Star opined that the album "reflects [Nina]'s mindset of thanking back the local music scene that has provided her blessings other lady acts can only dream of.

[216] Throughout her career, Nina has amassed six platinum or multi-platinum and one diamond album certifications by the Philippine Association of the Record Industry (PARI) which were based from pure physical sales.

[223] Her hit single "Love Moves in Mysterious Ways" held the record for longest running number-one OPM song, spending twelve consecutive weeks atop the Philippine charts in 2005.

[227][228] On January 18, 2009, she was recognized as Daily Winner on ABS-CBN's Magpasikat, a temporary replacement after the suspension of the noontime variety show Showtime, after performing a group dance with the G-Force.

(Roxanne Barcelo was also offered to take part in the song)[230] The following year, she was also honored as Singing Ambassador of Goodwill by the Center for Pop Music Philippines for performing for the less-fortunate institutions, fund-raising concerts and inspirational talks to students.

[239] In August 2009, she performed on YCONCON: Isang Araw Lang – The Sequel concert at the Araneta Coliseum, which supports Daniel Razon's "Free College Education" program.

[253] On June 27, she appeared as guest judge on Center for Pop's Music of Hope, an online variety competition show dedicated to help local frontliners.

[142] In an interview with SNN: Showbiz News Ngayon's Kris Aquino which aired in February 2009, Nina stated that she would file an estafa (fraud) case against Volante's parents, Evangeline and Oliver, for failing to settle their debts.