[1] After finishing high school at the age of 17 she studied biology and German language and literature at the TU Braunschweig to become a teacher.

In 1988 she was one of the editors who was involved in setting up RIAS-TV where she presented the evening news program Abendschau and later the breakfast TV show Frühstückfernsehen.

[2] Ruge finished nearly every edition of her show Leute heute with the quote Alles wird gut (Everything will turn out fine) which became her trademark and which she also used for some of her book titles.

[3] In the 1999 cinema film On the Wings of Love [de] Nina Ruge appeared in the role of Clarissa together with Maximilian Schell, Gudrun Landgrebe and Mathieu Carrière.

Together with her husband, top manager Wolfgang Reitzle, and Swiss billionaire Michael Pieper she has invested in the biotech startup Tomorrowlabs GmbH.