Antonino "Nino" Di Matteo (born 26 April 1961) is an Italian magistrate and prosecutor.

Since 2012, he is serving as president of the National Magistrates Association of Palermo and from 2019 to 2023 he has been a member of the High Council of the Judiciary.

He obtained a classical high school diploma from the Gonzaga Institute and graduated in law from the University of Palermo.

He entered the judiciary in 1991 as deputy prosecutor at the Anti-mafia division of Caltanissetta.

Having become a prosecutor in Palermo in 1999, he began to investigate the mafia massacres in which Giovanni Falcone, Paolo Borsellino and their guards were killed, as well as the murders of Rocco Chinnici and Antonino Saetta.