Their traditional icon of the outline of a young girl, first appearing on their Tennis album cover, was made from the image of model Dani Odom (née Kayla Kessel).

On 29 January 2006, the anime series Eureka Seven began to use the Nirgilis song "sakura" as an opening theme, which was later released as a single on March 1.

[2] In 2006, Nirgilis performed during the Sony Music Festival at Yoyogi Station in Tokyo and at Osaka's Osakajo Hall.

In September of the same year, Kōki Itō left the band; two months later, the "Brand New Day" single was the group's first release without either of its founding members.

[6] "kiseki" appeared as the first opening theme of the Birdy the Mighty Decode:02 anime series beginning on 31 December 2008, and was released as a single on 4 March 2009.

"[8] On June 29, 2021, nirgilis.net was updated with two new songs and a statement that the original members Moyo Satake and Kōki Itō reunited with Acchu Iwata.