The Nitta clan (新田氏, Nitta-shi) was one of several major families descended from the Seiwa Genji, and numbered among the chief enemies of the Hōjō clan regents, and later the Ashikaga shogunate.

Yoshishige was a landowner in the Nitta District of Kōzuke Province in present-day Gunma Prefecture.

Yoshishige supported Minamoto no Yoritomo (1147–1199) in the Battle of Ishibashiyama of 1180 against the Taira clan.

[1] The Nitta clan rose to importance in the early 13th century; they controlled Kozuke Province, and had little influence in Kamakura, the capital of the Kamakura shogunate, because their ancestor, Minamoto no Yoshishige had not joined his fellow clansmen in the Genpei War a century earlier.

They succeeded, in June 1333, in destroying the Bakufu's buildings in Kamakura.