In her youth, she learned graphic arts whiled working with her father, the painter Rafael Tufiño.
During her time at Academia de San Carlos, Tufiño met and was inspired by David Alfaro Siqueiros.
from the Universidad Nacional Autónoma de México, she moved to New York City.
In 1969, together with a group of artists, educators and activists, Tufiño founded El Museo del Barrio.
[1] Tufiño's ceramic murals have been commissioned for a number of public locations including the 103rd Street and Lexington Avenue subway station,[3] the Third Street Music School, and LaGuardia Community College.