The kibbutz was established after the Jewish National Fund purchased a 400-acre (1.6 km2) plot of land and a large house known as the "mansion" in 1942.

It experienced rapid expansion in the mid-2000s after being selected to temporarily house a large group of families evacuated from Gush Katif as part of the disengagement plan.

The neighbourhood was also the target of criticism by settlers and Israeli human-rights groups,[4][5] citing a lack of adequate housing and facilities.

They argued that governmental negligence resulted in a housing shortage, forcing large families to separate into multiple caravillas, and that basic infrastructure like a youth area, nursery, and synagogue were absent.

On 12 July 2012, the organization United With Israel delivered bomb shelters to the residents of Nitzan.