Most of her family returned to Nigeria after the end of the war in 1970, rejoining Agwu's father who had left the government service to become a farmer.

[2] Her dissertation, Using a Computer Laboratory Setting to Teach College Calculus, was supervised by Howard Cornelius Johnson.

[2][4] Agwu's interest in ethnomathematics stemmed from her development of a discrete mathematics course that would cover the college's requirement that students take a writing-intensive course.

She has written and co-authored some books with fellow reverends about her faith, like God's Own: The Genesis of Mathematical Story-Telling and Woman Thou Art Loosened: Escaping the Limitations of Femininity.

Nicholas Ogbonna had worked as a Red Cross volunteer for Biafra supervised by Agwu's mother.

It helps youth, women, and disabled people develop business and STEM skills by creating dolls connected to their cultural heritage with recycled materials.