"No Such Thing as Vampires" is the pilot episode of the American paranormal romance television drama Moonlight, which premiered on CBS on September 28, 2007.

Private investigator Mick St. John dreams of being interviewed by a woman off-camera, where he reveals that he is 84 years old,[3] and that unlike other vampires, he does not hunt women, children or innocents.

Chloe, a friend of the dead woman, attacks and slashes the neck of Ellis, whose blood Mick recognizes from the vial.

[4] The series was titled Twilight, and Koslow and Munson wrote the pilot, which Warner Bros. Television initially commissioned in January 2007 as a presentation lasting 14–20 minutes.

[8] David Greenwalt, creator of Miracles and co-creator of Angel, joined the staff in May 2007 as showrunner and executive producer alongside Silver.

[9] CBS hired Greenwalt during the pilot process to restructure the original concept by Koslow and Munson, however health reasons forced him to leave the series,[10] and Chip Johannessen took over showrunner duties in August 2007.

[11] All of the original actors save for the lead role of Mick St. John were recast in June 2007: Shannon Lucio, Rade Šerbedžija and Amber Valletta were originally cast in the roles of Beth Turner, Josef Kostan and Coraline Duvall respectively before Sophia Myles, Jason Dohring and Shannyn Sossamon replaced them.

[15] To promote the series, Silver, along with the rest of the main cast, attended the Comic-Con International in San Diego on July 27, 2007, where the show was featured.

[4] O'Laughlin felt that the whole cast's becoming "a little bit younger" especially affected the character Josef, as the originally chosen actor, Šerbedžija, was twice Dohring's age.

[20] Several critics compared it detrimentally with the television series Buffy the Vampire Slayer and its spinoff Angel,[21][22][23][24][25] as well as other vampire-related media, including Forever Knight,[3][23] Blood Ties,[25] The Night Stalker,[3] Dark Shadows and the works of Anne Rice.

[27] Rob Owen of the Pittsburgh Post-Gazette described the pilot as "a weak, generic private-eye drama with a vampire story overlay",[25] and Matthew Gilbert of the Boston Globe felt that it came close to a "full-on nightmare".

[29] Mary McNamara of the Los Angeles Times saw promise in the series, but remarked it got "lost between concept and execution, and instead of suspense we get silliness, as if the creators were determined to use only the clichés of both genres".

[22] Matthew Gilbert of the Boston Globe deprecated the chemistry between O'Loughlin and Myles as "artificial", and said that they "exchange lines of dialogue with a stilted rhythm and no natural flow".

[15] Travis Fickett of IGN praised the actors, however, and felt that O'Loughlin did "a decent job", and that Myles was "perhaps the most promising aspect of the show".