In 2018, she received a CogX UK Rising Star Award from Prime Minister Theresa May for "AI technology that will transform drug discovery to treat chronic diseases".

This extended to co-organising competitions to produce AIs which could tackle video games or generate new levels to fit the user, most notably using Super Mario.

[9] In 2017 Shaker co-founded GTN Ltd (Generative Tensorial Networks), a startup aiming to combine quantum computing and AI for drug discovery.

[10][11] Combining artificial intelligence with quantum models of published molecular structures may prove a novel and effective method to predict binding partners to disease regulators.

The company aims at integrating experts chemistry knowledge with advanced ML to enable rapid discovery of new chemical entities of desired properties.

[16] Shaker is often a speaker at AI events (including those aimed at women in the industry) and chairs the Institute of Electrical and Electronics Engineers Computational Intelligence: Games Technical Committee.