[5] The University of North Carolina hosted Jamie Hyneman and Adam Savage of Mythbusters for a program at the Smith Center with nearly 5,000 in attendance.

[5][6] East Carolina University and Go-Science hosted more than 2,000 participants[7] for the Eastern Regional Science Expo with exhibitions and demonstrations.

[1] Sponsors for the 2010 North Carolina Science Festival were Burroughs Wellcome Fund, Time Warner Cable and SAS (platinum level); Biogen Idec, Lenovo, Magellan Science, The News & Observer and UNC Health Care (gold level); Inspire Pharmaceuticals, NC STEM Community Collaborative and UNC School of Education (silver level); BB&T, The Research Triangle Park, Life Technologies Foundation, Dr. Nicholas B.

[9] Signature events included presentations by Neil deGrasse Tyson at UNC-Chapel Hill[10] and by Adam Savage and Jamie Hyneman at UNC-Charlotte [11] Signature events in 2013 included presentations by Alton Brown in Durham and Charlotte as well as a State Wide Star Party at 45 sites across the state.

[12] The 2017 festival was kicked off by Apollo 13 astronaut Jim Lovell and a proclamation by Roy Cooper naming April STEM Education Month in the state.