During the same period she made one separate trip transporting convicts from Britain to New South Wales, followed by a voyage for the EIC from China back to England.

Many boats observed the launch, as did many visitors at a gallery that Captain Robert Barker had erected.

She was part of a convoy under escort by HMS Seahorse that also included General Stuart, Manship, Sarah Christiana, Comet, Sovereign, Caledonia, Ann, Princess Mary, Varuna, Carron, Elizabeth, Monarch, and Friendship.

For her homeward bound trip she passed Sagar Island on 19 October and reached St Helena on 14 January 1803.

The Napoleonic Wars had broken out after the one-year Peace of Amiens, so her required a new letter of marque, which he had received on 20 June 1803.

[4] Northampton left Plymouth on 17 July, reached Rio de Janeiro on 23 September.

On 16 October she was three days out of Rio and in convoy with Lord Melville, Earl Spencer, Princess Mary, Anna, Ann, Glory, and Essex.

However, eight days later Northampton parted company, and being "very Crank, it is supposed put back to Bengal.

"[8] Northampton finally reached St Helena on 22 November, and arrived at the Downs on 9 February 1805.

She was in convoy with Sarah Christiana, Ann, Union, Diana, Sir William Pulteney, and Glory.

Homeward bound, She passed Saugor on 3 June, reached St Helena on 28 September.

Several other East Indiamen also suffered damage and Walpole, Sandlands, master, was driven aground.

[12] On 24 December 1808, 15 seamen from Northampton's crew were delivered to the Royal Navy receiving ship HMS El Corso at Gravesend.

Returning home, she visited Point de Galle on 22 February 1810, reached St Helena of 4 May, and arrived at the Downs on 6 July.

In April, Lloyd's List reported that they had been seen well at 35°42′N 15°0′W / 35.700°N 15.000°W / 35.700; -15.000 (approximately 400 km NNE of Funchal), and under the escort of the frigate HMS Curacoa.

[16] While Northampton, Euprates, and Monarch were in the Channel, they encountered the British frigate Nayaden, which signalled that a flotilla of five French ships of the line that had escaped from Lorient were in the vicinity and that she had exchanged some shots with them.

[17] She sprang a leak three times while descending the Bengal River and had to return to Calcutta to be docked.

Furthermore, with the wars with France and America drawing to a close, her master for this voyage did not acquire a letter of marque.

[23] Captain Charles Tebbut (or Tebbutt) left Portsmouth on 16 May 1818, bound for Madras and Bengal.

Homeward bound, she passed Sagar on 22 January 1819, reached St Helena on 26 March, and arrived at the Downs on 27 June.

A list of "Licensed India ships" showed Northampton, Tebbutt, master, Palmer, owner, sailing to Bencoolen on 17 November 1819.

Instead, Captain Charlton sailed from London on 13 December 1819, with 257 emigrants, bound for South Africa under the British Government's 1820 Settlers scheme.