It is located in a dedicated median along Huntington Avenue in Boston, between Opera Place and Forsyth Street, and is adjacent to the Krentzman Quad on the campus of Northeastern University.

It is the first surface-level stop going outbound along the Green Line E branch; trolleys rise from a portal located between Opera Place and Gainsborough Street and continue along the surface down Huntington Avenue towards Mission Hill.

With the completion of the tunnel, Opera Place became an important short turn location; a siding was constructed adjacent to the inbound track.

[4] Like other surface stops on the median-reservation section of the line, Northeastern University station had bare asphalt platforms.

The line was cut back to Symphony on March 21, 1980; it was re-extended to Northeastern (using LRVs) on June 21 and Brigham Circle on September 20.