Novoisayevo (Russian: Новоисаево; Bashkir: Яңы Исай, Yañı İsay) is a rural locality (a village) in Novosubayevsky Selsoviet, Nurimanovsky District, Bashkortostan, Russia.

Novoisayevo is located 30 km southeast of Krasnaya Gorka (the district's administrative centre) by road.

Ryatush is the nearest rural locality.

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