Novotyryshkino (Russian: Новотырышкино) is a rural locality (a selo) and the administrative center of Novotyryshkinsky Selsoviet, Smolensky District, Altai Krai, Russia.

[2] There are 22 streets in the locality.

Novotyryshkino is located 38 km southwest of Smolenskoye (the district's administrative centre) by road.

Sychyovka is the nearest rural locality.

This Smolensky District, Altai Krai location article is a stub.